Systems Proteomics: Quantitative Studies of Protein Dynamics (Virtual)

Systems Proteomics: Quantitative Studies of Protein Dynamics (Virtual)

Apr 23, 2021 - 3:10 PM
to , -

Dr. Justin Walley, Department of Plant Pathology and Microbiology, ISU

Host: Dr. Young-Jin Lee

Proteins make or regulate nearly every component of a cell. Therefore, a comprehensive knowledge of proteomic states is essential for understanding biological systems. I will present my groups work at refining analytical and computational methods that enable deep coverage and high throughput quantification of proteins and post-translational modifications (phosphorylation, acetylation, ubiquitination, etc.) in plants. I will highlight our work on determining protein-protein interactions using proximity labeling as well as how we are using quantitative proteomics to reveal plant hormone response networks. Finally, I will discuss our work examining the maize innate immune response to the highly virulent fungal pathogen Cochliobolus carbonum.  Specifically, this work focuses on how HC-toxin, a naturally occurring histone deacetylase inhibitor, promotes pathogen virulence towards maize.


Event password: YHasrd5E7R6 (if needed)