Yan Zhao

Yan Zhao

Position
  • Professor
Department
  • Chemistry
We create biomimetic materials and catalysts through organic synthesis and molecular engineering.

Contact

Contact Info

3101D Hach, 2438 Pammel Dr
Ames
,
Iowa
50011-1079
Social Media and Websites

Postdoctoral Openings in the Zhao group | Department of Chemistry (iastate.edu)


The biological world has unparalleled abilities to control structures, functions, reactions, and energy transfer with great efficiency and accuracy. We are interested in biomimetic chemistry to “abstract good design from nature.” One of our main research goals is to design molecules that functionally mimic certain biological systems, and in turn to prepare molecules, polymers, and materials that have useful and superior properties. Our imprinted nanoparticles mimic natural antibodies in their molecular recognition of small-molecule drugs, peptides, and carbohydrates. They serve as excellent supramolecular hosts, specific biomimetic sensors, and smart materials useful for chemistry and biology.  Our enzyme-mimetic catalysts carry out highly selective chemical transformations in water under mild conditions. With tunable chiral space near the catalytic center, our synthetic aldolase enables poor chiral (prolinamide) catalysts to achieve up to 99% ee and even racemic catalysts >70% ee.      


For a detailed description of our research, see: https://www.chem.iastate.edu/yan-zhao-research-interests

List of publications: https://www.chem.iastate.edu/yan-zhaos-publications

Recent group photos: https://www.chem.iastate.edu/zhao-group