College of Liberal Arts and Sciences

Department of Chemistry

Yeon Kyun Shin

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Selected Publications

  1. Kweon, D.H., Kim, C.S. and Shin, Y.K. (2003) Regulation of neuronal SNARE assembly by the membrane. Nat. Struct. Biol. 10, 440-447.
  2. Kweon, D.H., Kim, C.S. and Shin, Y.K. (2003) Insertion of the membrane-proximal region of the neuronal SNARE coiled coil into the membrane. J. Biol. Chem. 278, 12367-12373.
  3. Kim, C.S., Kweon, D.H. and Shin, Y.K. (2002) Membrane topologies of neuronal SNARE folding intermediates. Biochemistry 41, 10928-10933.
  4. Kweon, D.H., Kim, C.S. and Shin, Y.K. (2002) The membrane-dipped neuronal SNARE complex: a site-directed spin labeling electron paramagnetic resonance study. Biochemistry 41, 9264-9268.
  5. Zhang, F., Chen, Y., Kweon, D.H., Kim, C.S. and Shin, Y.K. (2002) The four-helix bundle of the neuronal target membrane SNARE complex is neither disordered in the middle nor uncoiled at the C-terminal region. J. Biol. Chem. 277, 24294-24298.
  6. Kweon, D.H., Chen, Y., Zhang, F., Poirier, M., Kim, C.S. and Shin, Y.K. (2002) Probing domain swapping for the neuronal SNARE complex with electron paramagnetic resonance. Biochemistry 41, 5449-5452.
  7. Epand, R.F., Yip, C.M., Chernomordik, L.V., LeDuc, D.L., Shin, Y.K. and Epand, R.M. (2001) Self-assembly of influenza hemagglutinin: studies of ectodomain aggregation by in situ atomic force microscopy. Biochim. Biophys. Acta 1513, 167-175.
  8. Leikina, E., LeDuc, D.L., Macosko, J.C., Epand, R., Shin, Y.K. and Chernomordik, L.V. (2001) The 1-127 HA2 construct of influenza virus hemagglutinin induces cell-cell hemifusion. Biochemistry 40, 8378-8386.
  9. Xiao, W., Poirier, M.A., Bennett, M.K. and Shin, Y.K. (2001) The neuronal t-SNARE complex is a parallel four-helix bundle. Nat. Struct. Biol. 8, 308-311.
  10. LeDuc, D.L. and Shin, Y.K. (2000) Insights into a structure-based mechanism of viral membrane fusion. Biosci. Rep. 20, 557-570.
  11. LeDuc, D.L., Shin, Y.K., Epand, R.F. and Epand, R.M. (2000) Factors determining vesicular lipid mixing induced by shortened constructs of influenza hemagglutinin. Biochemistry 39, 2733-2739.
  12. Xiao, W., Brown, L.S., Needleman, R., Lanyi, J.K. and Shin, Y.K. (2000) Light-induced rotation of a transmembrane alpha-helix in bacteriorhodopsin. J. Mol. Biol. 304, 715-721.
  13. Smith, T., McCracken, J., Shin, Y.K. and DeWitt, D. (2000) Arachidonic acid and nonsteroidal anti-inflammatory drugs induce conformational changes in the human prostaglandin endoperoxide H2 synthase-2 (cyclooxygenase-2). J. Biol. Chem. 275, 40407-40415.
  14. Macosko, J.C., Pio, M.S., Tinoco, I., Jr. and Shin, Y.K. (1999) A novel 5 displacement spin-labeling technique for electron paramagnetic resonance spectroscopy of RNA. RNA 5, 1158-1166.
  15. Rombel, I., Peters-Wendisch, P., Mesecar, A., Thorgeirsson, T., Shin, Y.K. and Kustu, S. (1999) MgATP binding and hydrolysis determinants of NtrC, a bacterial enhancer-binding protein. J. Bacteriol. 181, 4628-4638.
  16. Hwang, I., Thorgeirsson, T., Lee, J., Kustu, S. and Shin, Y.K. (1999) Physical evidence for a phosphorylation-dependent conformational change in the enhancer-binding protein NtrC. Proc. Natl. Acad. Sci. USA 96, 4880-4885.
  17. Ottemann, K.M., Xiao, W., Shin, Y.K. and Koshland, D.E., Jr. (1999) A piston model for transmembrane signaling of the aspartate receptor. Science 285, 1751-1754.