College of Liberal Arts and Sciences

Department of Chemistry

Mei Hong

Biophysical chemistry, protein structure, solid-state NMR

Home | Research Interests | Group Page | Selected Publications

For complete publication list, see group web site.

  1. S.D. Cady and M. Hong, "Amantadine-Induced Conformational and Dynamical Changes of the Influenza M2 Transmembrane Proton Channel", Proc. Natl. Acad. Sci., 105, 1483-1488 (2008).
  2. M. Tang, A. J. Waring, R. I. Lehrer and M. Hong, "Effects of Guanidinium-Phosphate Hydrogen Bonding on the Membrane-Bound Structure and Activity of an Arginine-Rich Membrane Peptide from Solid-State NMR", Angew. Chem. Int. Ed., in press (2008).
  3. S.D. Cady, C. Goodman, C. Tatko, W.F. DeGrado, and M. Hong, "Determining the Orientation of Uniaxially Rotating Membrane Proteins Using Unoriented Samples: a 2H, 13C, and 15N Solid-State NMR Investigation of the Dynamics and Orientation of a Transmembrane Helical Bundle", J. Am. Chem. Soc. 129, 5719-5729 (2007).
  4. M. Tang, A. J. Waring and M. Hong, "Phosphate-Mediated Arginine Insertion Into Lipid Membranes and Pore Formation by a Cationic Membrane Peptide from Solid-State NMR", J. Am. Chem. Soc. 129, 11438-11446 (2007).
  5. W. Luo, R. Mani and M. Hong, "Sidechain Conformation and Gating of the M2 Transmembrane Peptide Proton Channel of Influenza A Virus from Solid-State NMR", J. Phys. Chem. B. 111, 10825-10832 (2007).
  6. M. Hong, "Structure, Topology, and Dynamics of Membrane Peptides and Proteins from Solid-State NMR Spectroscopy", J. Phys. Chem. B. feature article, 111, 10340-10351 (2007).
  7. T. Doherty, A. J. Waring and M. Hong, "Membrane-bound conformation and topology of Tachyplesin-1 by solid-state NMR spectroscopy", Biochemistry, 45, 13323-13330 (2006).
  8. R. Mani, S.D. Cady, M. Tang, A.J. Waring, R.I. Lehrer, and M. Hong, "Membrane-dependent oligomeric structure and pore formation of a β-hairpin antimicrobial peptide in lipid bilayers from solid-state NMR", Proc. Natl. Acad. Sci. U.S.A., 103, 16242-16247 (2006).
  9. M. Hong, "Solid-State NMR Studies of the Structure and Dynamics of Disordered and Membrane-Bound Peptides and Proteins", Acct. Chem. Res., 39, 176-183 (2006).
  10. W. Luo and M. Hong, "Determination of the Oligomeric Number and Intermolecular Distances of Membrane Protein Assemblies by Anisotropic 1H-Driven Spin Diffusion NMR", J. Am. Chem. Soc. 128, 7242-7251 (2006).
  11. M. Tang, A.J. Waring, R.I. Lehrer, and M. Hong, "Orientation of a beta-hairpin Antimicrobial Peptide in Lipid Bilayers from 2D Dipolar Chemical-Shift Correlation NMR", Biophys. J. 90, 3616-3624 (2006).
  12. M. Tang, A.J. Waring, and M. Hong, "Intermolecular Packing and Alignment of a beta-Hairpin Peptide from 2D Solid-State NMR", J. Am. Chem. Soc. 127, 13919-13927 (2005).
  13. W. Luo, X.L. Yao and M. Hong, "Evidence of Large Structure Rearrangement of Colicin Ia Channel Domain Due to Membrane Binding from 2D 13C Spin Diffusion NMR", J. Am. Chem. Soc. 127, 6402-8 (2005).
  14. S. Wi, H. Sun, E. Oldfield and M. Hong, "Solid-State NMR and Quantum Chemical Investigations of 13C. Shielding Tensor Magnitudes and Orientations in Peptides: Determining Φ and Ψ Torsion Angles", J. Am. Chem. Soc., 127, 6451-6458 (2005).
  15. J.J. Buffy, A.J. Waring, and M. Hong, "Determination of Peptide Oligomerization in Lipid Bilayers Using 19F Spin Diffusion NMR", J. Am. Chem. Soc., 127, 4477-4483 (2005).